Norethisterone (or norethindrone) (or 19-nor-17α-ethynyltestosterone) is a molecule used in some combined oral contraceptive pills and in some progestogen only pills. It is a progestogen and can be used to treat premenstrual syndrome, painful periods, abnormal heavy bleeding, irregular periods, menopausal syndrome (in combination with oestrogen), or to postpone a period. Norethindrone was the first orally highly active progestin to be synthesized. It was synthesized for the first time by chemists Luis Miramontes, Carl Djerassi, and George Rosenkranz at Syntex in Mexico City in 1951.[1] It was the progestin used in one of the first two oral contraceptives. It is often used as the related ester, norethisterone acetate.
References
- ^ Djerassi C, Miramontes L, Rosenkranz G, Sondheimer F (1954). "Steroids. LIV. Synthesis of 19-Nor-17α-ethynyltestosterone and 19-Nor-17α-methyltestosterone" (abstract page). J Am Chem Soc 76 (16): 4089–4091. doi:10.1021/ja01645a009. http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/1954/76/i16/f-pdf/f_ja01645a010.pdf.
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Categories: Syntex | Progestagens |
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PR Newswire (press release)
A randomized, double-blind, double-dummy, placebo-controlled multicenter study assessing the effects of norethindrone acetate and ethinyl estradiol in the ...
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Sun, 19 Jul 2009 18:44:53 GM
Dosage . norethindrone. .
Q. I'm "only" 28, but I'm taking Activella to get my hormones back to normal after they got out of whack from the Depo-Provera shot. Anyway, I'm curious if taking one or more of these would prevent pregnancy like Plan B does. Also wondering about the differences and similarities between the chemical properties of levonorgestrel and estradiol/norethindrone acetate. Thanks.
Asked by A Jen In Progress - Tue Oct 10 18:48:24 2006 - - 1 Answers - 0 Comments
A. No, estrogen cannot be used as Plan B. Plan B is made up of artificial progestin not estrogen. Two different hormones. If you need Plan B, go to a pharmacy!
Answered by piepiepie - Tue Oct 10 20:01:27 2006
